2018年

2018/04/20 (Fri) Cell Rep. 2018 Feb 27;22(9):2431-2441. S. aureus Evades Macrophage Killing through NLRP3-Dependent Effects on Mitochondrial Trafficking. PubMed

2018/03/30 (Fri) Immunity. 2018 Feb 20;48(2):350-363.e7. A Macrophage Colony-Stimulating-Factor-Producing γδ T Cell Subset Prevents Malarial Parasitemic Recurrence. PubMed

2018/03/16 (Fri) Cell Rep. 2017 Jul 5;20(1):124-135. RORα Induces KLF4-Mediated M2 Polarization in the Liver Macrophages that Protect against Nonalcoholic Steatohepatitis. PubMed

2018/03/02 (Fri) Immunity. 2018 Feb 20;48(2):299-312.e5. Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity. PubMed

2018/01/26 (Fri) Immunity. 2018 Jan 16;48(1):59-74.e5. Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation. PubMed

2018/01/12 (Fri) Immunity. 2017 Dec 19;47(6):1154-1168.e6. White Adipose Tissue Is a Reservoir for Memory T Cells and Promotes Protective Memory Responses to Infection. PubMed

2017年

2017/12/08 (Fri) Cell Rep. 2017 Feb 21;18(8):2045-2057. ER Stress Protein CHOP Mediates Insulin Resistance by Modulating Adipose Tissue Macrophage Polarity. PubMed

2017/11/24 (Fri) Cell Host Microbe. 2017 Sep 13;22(3):302-316.e7. Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages. PubMed

2017/11/10 (Fri) Cell Metab. 2017 Aug 1;26(2):394-406.e6. Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation. PubMed

2017/10/20 (Fri) Cell Rep. 2017 Oct 10;21(2):403-416. A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response. PubMed

2017/10/06 (Fri) Cell. 2017 Oct 5;171(2):372-384.e12. Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity. PubMed

2017/09/22 (Fri) Nat Commun. 2017 Aug 18;8(1):286.
CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors. PubMed

2017/09/08 (Fri) Nat Commun. 2017 May 16;8:15287. Exosomes maintain cellular homeostasis by excreting harmful DNA from cells. PubMed

2017/08/04 (Fri) Nat Commun. 2017 Jan 27;8:14147. A-FABP mediates adaptive thermogenesis by promoting intracellular activation of thyroidhormones in brown adipocytes. PubMed

2017/07/21 (Fri) Science. 2017 May 5;356(6337):513-519. Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages. PubMed

2017/07/07 (Fri) Cell Metab. 2016 Feb 9;23(2):315-23. PTH/PTHrP Receptor Mediates Cachexia in Models of Kidney Failure and Cancer. PubMed

2017/06/23 (Fri) Nat Immunol. 2017 Jun;18(6):654-664. A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity. PubMed

2017/06/09 (Fri) Cell Metab. 2017 Jun 6;25(6):1374-1389.e6. Age-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence. PubMed

2017/05/26 (Fri) Cell. 2016 Feb 25;164(5):896-910. NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria. PubMed

2017/05/12 (Fri) Nat Immunol. 2017 May;18(5):519-529. The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity. PubMed

2017/04/21 (Fri) J Clin Cell Immunol. 2016 Oct;7(5).ER Stress-induced Inflammasome Activation Contributes to Hepatic Inflammation and Steatosis. PubMed

2017/04/07 (Fri) J Hepatol. 2013 Feb;58(2):358-64. Pharmacological inhibition of adipocyte fatty acid binding protein alleviates both acute liver injury and non-alcoholic steatohepatitis in mice. PubMed

2017/03/24 (Fri) J Immunol. 2017 Mar 1;198(5):2156-2164. MLKL Activation Triggers NLRP3-Mediated Processing and Release of IL-1β Independently of Gasdermin-D. PubMed

2017/03/10 (Fri) Sci Transl Med. 2016 Sep 28;8(358):358ra126. Prevention of atherosclerosis by bioactive palmitoleate through suppression of organelle stress and inflammasome activation. PubMed

2017/02/17 (Fri) Nat Immunol. 2016 Sep;17(9):1046-56. C13orf31 (FAMIN) is a central regulator of immunometabolic function. PubMed

2017/02/03(Fri) Nat Immunol. 2016 Dec;17(12):1459-1466. Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression. PubMed

2017/01/20 (Fri) Cell. 2016 Jul 28;166(3):624-36. Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan. PubMed

2016年

2016/12/16 (Fri) Cell. 2016 Jun 30;166(1):63-76. Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming. PubMed

2016/12/02 (Fri) Sci Rep. 2016 Oct 12;6:35016. TRPM2 regulates TXNIP-mediated NLRP3 inflammasome activation via interaction with p47 phox under high glucose in human monocytic cells. PubMed

2016/11/18 (Fri) Immunity. 2016 Nov 15;45(5):1093-1107. Cross-Regulation of Two Type I Interferon Signaling Pathways in Plasmacytoid Dendritic Cells Controls Anti-malaria Immunity and Host Mortality. PubMed

2016/11/04 (Fri) Nat Commun. 2016 Oct 25;7:13280. PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation. PubMed

2016/10/21 (Fri) Cell Rep. 2015 Jul 7;12(1):102-15. mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation. PubMed

2016/10/07 (Fri) Nat Microbiol. 2016 Feb 24;1:15034. Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis. PubMed

2016/09/23 (Fri) Nat Med. 2016 Sep;22(9):1002-12. NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages. PubMed

2016/09/9 (Fri) Cell. 2016 Aug 25;166(5):1117-1131. Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche. PubMed

2016/08/26 (Fri) Nat Immunol. 2016 Sep;17(9):1037-45 Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense. PubMed

2016/07/15 (Fri) Cell Metab. 2016 Jan 12;23(1):155-64. IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome. PubMed

2016/07/01 (Fri) Nature. 2016 May 18;533(7604):552-6. Access of protective antiviral antibody to neuronal tissues requires CD4 T-cell help. PubMed

2016/06/17 (Fri) Nature. 2015 Oct 29;526(7575):660-5. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. PubMed

2016/06/03 (Fri) Nature. 2016 Apr 21;532(7599):394-7. NOD1 and NOD2 signalling links ER stress with inflammation. PubMed

2016/05/20 (Fri) Nat Immunol. 2016 May;17(5):583-92. T cell-intrinsic ASC critically promotes TH17-mediated experimental autoimmune encephalomyelitis. PubMed

2016/04/22 (Fri) Cell. 2015 Dec 3;163(6):1413-27. CD5L/AIM regulates lipid biosynthesis and retrains Th17 cell pathogenicity. PubMed

2016/04/01 (Fri) Nat Med. 2014 Nov;20(11):1327-33. De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells. PubMed

2016/03/18 (Fri) Nature. 2016 Feb 18;530(7590):354-7. NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux. PubMed

2016/03/04 (Fri) Nat Immunol. 2016 Jan;17(1):76-86. Interferon and IL-27 antagonize the function of group 2 innate lymphoid cells and type 2 innate immune  responses. PubMed

2016/02/12 (Fri) Cell Metab. 2016 Jan 12;23(1):179-93. Reduced Insulin Production Relieves Endoplasmic Reticulum Stress and Induces β Cell Proliferation. PubMed

2016/02/05 (Fri) Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):E7239-48. CD11b regulates obesity-induced insulin resistance via limiting alternative activation and proliferation of adipose tissue macrophages. PubMed

2016/01/15 (Fri) Nature. 2015 Dec 24;528(7583):565-9. Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection. PubMed